Disease X: Hunting The Next Pandemic — BBC2 review highlights AI's promise and the enduring virus threat
Roland White soberly assesses a documentary that warns of future outbreaks while detailing how surveillance and AI could accelerate responses.

A BBC2 documentary, Disease X: Hunting The Next Pandemic, opens with a stark warning that another outbreak could arrive despite lessons from Covid-19. Presenter Dr Chris van Tulleken, a physician at the Hospital for Tropical Diseases in London, says Covid may have just been a warning shot and that experts fear worse is coming, though they are unsure what form it will take.
The program then surveys historical signals of misattribution and animal sources, underscoring how easily a novel pathogen can leap across species. It notes that bird flu H5N1 has infected mammals in Texas, illustrating how transmission can cross into unexpected hosts. It recounts Malaysia’s 1998 cull of about a million pigs after fears of a deadly fever, a response that later proved the pigs were not the source in the broader epidemiological picture. In Bangladesh, a similar outbreak traced to fruit bats contaminating date palm sap shows how local practices can influence how a virus spreads. The message is clear: the next big outbreak could emerge from a doorway we cannot predict, and the world must stay vigilant.
On the upside, the show highlights a suite of defenses already in play. There is a daily meeting at the World Health Organization that monitors potential outbreaks, tracking unusual coughs or clusters of illness around the globe. The program also features Glasgow University’s Centre for Virus Research, where researchers use a handheld device to identify previously undiscovered viruses. Scientists then employ artificial intelligence to examine the structure of the viruses, information that helps guide vaccine design. The AI-driven analysis is described as taking roughly five minutes, a dramatic acceleration over traditional lab timelines.
Yet the report is careful to temper optimism with realism. AI is presented as a powerful tool to speed detection and vaccine development, but it does not supplant the need for robust public-health systems, governance, and supply chains. The narrative repeatedly emphasizes that policy decisions, funding, and logistics will shape whether a rapid scientific breakthrough translates into effective protection for populations. In a closing line that echoes the documentary’s tension, the reviewer notes that if it comes to a straight contest between the frailties of human governance and a crafty new virus, the virus may still prevail.
Overall, the review frames Disease X as a balanced exploration of risk and resilience within pandemic preparedness. It underscores the importance of global surveillance and rapid diagnostic tools, while highlighting the potential and limits of AI in accelerating vaccine development. The documentary, while plainly entertainment for a broad audience, offers a sober, evidence-based portrait of the front lines in pandemic preparedness and the ongoing concern that the next outbreak could arrive sooner than expected.