Fainting spells may signal heart rhythm problems or mini-strokes, doctors warn; guidance on evaluation and pernicious anaemia
Medical guidance outlines tests for fainting episodes and explains how pernicious anaemia causes vitamin B12 deficiency.

A sudden blackout can be brief, but doctors urge taking such episodes seriously, especially in older adults. The most likely explanation is a cardiovascular problem, such as an abnormal heart rhythm that briefly lowers blood pressure and reduces blood flow to the brain. That pattern can cause a temporary loss of consciousness without a heart attack, but it may signal an underlying condition that needs assessment.
Doctors typically begin with an electrocardiogram, or ECG, to check the heart’s electrical activity. If the initial reading is normal, a wearable monitor kept in place for up to a week may be used to capture rhythms over time. Because the episode described did not occur with exertion, an exercise ECG test is not always indicated at the outset. While a rhythm problem can be serious and raise stroke risk in some cases, a fainting spell is not itself a heart attack.
If an abnormal rhythm is found or suspected but the ECG is inconclusive, doctors may expand testing to determine whether blood flow to the brain was affected in other ways. In particular, an ultrasound examination of the neck arteries can reveal cholesterol build-ups that might contribute to transient blockages. Separately, an MRI of the brain can assess arteries within the brain itself. The takeaway is that a prompt, proactive approach is essential: make an appointment with a GP promptly rather than waiting to see if fainting recurs.
In some cases, a fainting spell may be related to a transient ischemic attack, or TIA, sometimes described as a mini-stroke. TIAs occur when blood flow in a vessel that supplies the brain is briefly interrupted. They typically resolve quickly and do not cause lasting damage, but they are a warning sign that a full stroke could occur if risk factors are not addressed. If heart tests come back clear, doctors often pursue a neck artery ultrasound and a brain MRI to search for sources of small, artery-blocking clots. Proactive evaluation is key because early detection and treatment can reduce future risk.
Two months ago, a reader named Jane Morris described tingling hands and feet, accompanied by cold, pale hands. She was diagnosed with vitamin B12 deficiency, or pernicious anaemia, after medical evaluation. Pernicious anaemia is the most common cause of B12 deficiency and results from an autoimmune reaction that damages the cells that produce intrinsic factor, a protein required for absorbing B12 in the small intestine. Without intrinsic factor, the body cannot absorb enough B12, a vitamin vital for brain, nerve and blood cell function.
B12 is found in eggs, meat and fish and is normally absorbed with the help of intrinsic factor. When intrinsic factor production is impaired, symptoms such as tingling, numbness, cold extremities, fatigue and brain fog can occur. The condition is treated with regular B12 injections, typically given four times a year for life. Recovery depends on how long symptoms have persisted before treatment began and how severe the nerve involvement is. Some patients experience meaningful improvement within a few months, while others may take up to a year or longer to recover. In earlier-diagnosed cases, return of sensation and improved circulation in hands and feet is common over time, though long-standing nerve damage may limit full recovery.
The cause of pernicious anaemia often lies in the immune system attacking stomach cells or the factors needed to aid absorption, sometimes associated with gastritis or chronic stomach issues from medications such as NSAIDs or certain infections. Although the neuropathic symptoms can improve with treatment, the underlying autoimmune process requires ongoing management. The important message for readers is that persistent tingling or unusual numbness warrants medical evaluation, as timely B12 therapy can prevent further nerve damage and support recovery.
For anyone who experiences a fainting episode, the guidance remains to contact a healthcare provider promptly. Early assessment, including ECG and possibly extended rhythm monitoring, can identify treatable conditions. When B12 deficiency is diagnosed, adherence to the prescribed injection schedule and follow-up nutritional assessment are important to sustain nerve and blood function over time. Vigilance regarding these health issues, alongside regular medical follow-up, can help reduce the risk of more serious outcomes and improve quality of life.