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The Express Gazette
Saturday, December 27, 2025

New study probes why COVID vaccines may trigger heart inflammation in some people

Researchers describe a potential immune-linked mechanism and highlight a demographic with higher signals, while stressing that vaccines remain essential.

Health 5 days ago
New study probes why COVID vaccines may trigger heart inflammation in some people

A new study has identified a possible mechanism behind rare cases of heart inflammation after mRNA COVID-19 vaccination, noting a stronger signal in one demographic. The researchers describe the condition as heart inflammation that appears in a small subset of recipients following vaccination. They caution that the event remains uncommon and that the benefits of vaccination still far outweigh the risks for the vast majority of people.

The study points to an immune response triggered by the vaccine that, in susceptible individuals, may mount an inflammatory reaction in heart tissue. The authors say the pattern emerges in post-dose monitoring and is more pronounced in the identified demographic, though they emphasize that more research is needed to confirm the mechanism and determine who is at higher risk.

Researchers stressed that the information should be interpreted in the context of ongoing vaccine safety surveillance. Public health officials have documented rare cardiac events after vaccination, and the new findings aim to help clinicians recognize patterns and guide monitoring, without undermining the overall public health benefit of vaccines.

Health experts are calling for continued vaccination, noting that the risk of heart inflammation remains far lower than the risk posed by COVID-19 itself and its potential complications. People who recently received an mRNA vaccine and develop chest pain, shortness of breath, fainting, or an irregular heartbeat in the days or weeks after vaccination should seek prompt medical attention. Clinicians may consider reviewing patients' medical history and current medications to assess risk.

Another patient having blood pressure measured

Beyond the specific post-vaccine signal, health professionals emphasize overall cardiovascular health as a key component of reducing risk for heart disease. In related health reporting, experts note that simple lifestyle changes—such as maintaining a healthy diet, staying physically active, avoiding tobacco, and controlling blood pressure—can meaningfully reduce the risk of heart attack for millions.

As the study circulates within the medical community, researchers plan further work to confirm the mechanism and to identify any measurable markers that could help predict risk before vaccination. In the meantime, experts urge that vaccination decisions continue to be based on a careful assessment of individual risk and community protection against COVID-19.

Woman blowing nose during COVID-19 variant awareness


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