NFL Week 16 betting: Vikings seek third straight win vs. Giants; Chargers aim to stay in pace vs. Cowboys
Vikings +3 at Giants; Chargers +2.5 at Cowboys; betting picks from New York Post Betting
In Week 16, the New York Post Betting Bettor’s Guide highlights two notable lines. The Minnesota Vikings are 3-point underdogs against the New York Giants, and the Los Angeles Chargers are 2.5-point underdogs against the Dallas Cowboys.
Minnesota has won two straight and is looking to carry momentum into MetLife against a Giants team that appeared listless in a 2025 loss to the Commanders, who started backup Marcus Mariota. Giants rookie Jaxson Dart has regressed since returning from a concussion, and Brian Flores’ exotic defense is expected to pressure him again. The Vikings figure to lean on Justin Jefferson and a power running attack to exploit a vulnerable Giants run defense.
On the other side, the Chargers (10-4) have won three straight and are chasing a fifth consecutive victory. Los Angeles has already knocked off the Super Bowl participants in back-to-back weeks and also defeated the Raiders, providing momentum for a late-season push to keep pace in the AFC West behind the division-leading Broncos. Dallas’ defense has regressed in recent weeks, and questions about the Cowboys' playoff status could loom large entering kickoff. If Dallas remains in contention, Los Angeles could sneak out of Dallas with a win and stay in the mix for the conference title.
Matt Ehalt — the Post Betting editor behind the guide — has built a reputation for NFL wagering insight. The column lists a 2025 record of 10-18-2 and a 2-0 showing last week, reflecting his focus on spread bets across the season.