Week 3 of 2025 NFL season set to showcase a full slate as Dolphins-Bills headlines
Dolphins visit Bills for an 8:15 p.m. ET kickoff as early-league passing leaders emerge; Chiefs and Giants aim to snap winless starts in a weekend packed with key matchups.
Week 3 of the 2025 NFL season features a full slate of games, headlined by the Miami Dolphins’ trip to Buffalo to face the Bills in an 8:15 p.m. ET kickoff as Miami tries to avoid dropping to 0-3 against Buffalo. Through two weeks, league passing leader status was led by New York Giants quarterback Russell Wilson with 618 yards, followed by Indianapolis Colts quarterback Daniel Jones with 588, as both teams looked to build momentum early in the season.
Sunday’s schedule across the league features a host of pivotal matchups, including Green Bay at Cleveland, Indianapolis at Tennessee, Cincinnati at Minnesota, Pittsburgh at New England, Los Angeles Rams at Philadelphia, New York Jets at Tampa Bay, Las Vegas at Washington, Atlanta at Carolina, Houston at Jacksonville, Denver at Los Angeles, New Orleans at Seattle, Dallas at Chicago, Arizona at San Francisco, and Kansas City at the New York Giants in a prime-time showdown. The weekend closes with Detroit visiting Baltimore on Monday night, a game that will test both teams’ early-season adjustments as the calendar turns to Week 3.
Beyond the marquee game, the league will be watching how teams respond after two weeks of play. The Kansas City Chiefs and the Giants both entered Week 3 seeking to shake off early-season struggles, each looking to avoid falling to 0-3. In the passing game, Wilson’s early leadership in yards highlighted how quickly teams can lean on veteran playmakers as they adjust to new schemes and rising expectations. Jones, meanwhile, had to navigate another week of early-season responsibilities with the Colts looking to show they can compete in a stacked AFC field.
One of the Sunday highlights features Jacksonville hosting Houston at 1 p.m. ET, with Trevor Lawrence expected to lead the Jaguars in what could be a pivotal moment for an offense aiming to capitalize on its early-season opportunities. The Lions’ matchup with Baltimore on Monday night will offer a closer look at Jahmyr Gibbs’ ability to impact a powerful Detroit ground game as the schedule shifts into Week 3’s late window. The Sunday slate also includes a trip to Seattle for New Orleans and a meeting in San Francisco as Arizona visits the 49ers, rounding out a weekend designed to test teams’ depth and adaptability as the NFL moves deeper into autumn.
As Week 3 unfolds, teams will be aiming to establish early-season rhythm and momentum while sorting out personnel and matchup dynamics that could shape the rest of the campaign. With a full slate of games, several clubs will have the chance to set a turning point in what many expect to be a highly competitive 2025 season. Fans can expect a mix of established rivals and emerging storylines to define Week 3 actions, from Thursday-night-style intensity in Buffalo to late-season-like pressure in prime time.