Week 4 NFL early predictions: Sharps target lines ahead of kickoff
Washington Commanders on the road as 2-point favorites; Eagles favored at Tampa Bay; bettors eye top targets including Noah Igbinoghene, Jeremy McNichols and Deebo Samuel Sr.

Sharps were quick to bet Week 4 lines as soon as Sunday night, with Caesars Sportsbook listing the Washington Commanders as 2-point favorites on the road against the Atlanta Falcons.
Among the targets in the Week 4 preview are players Noah Igbinoghene, Jeremy McNichols and Deebo Samuel Sr., according to the New York Post Betting. The column noted their bets as part of its best-bets and picks to target before lines move. The preview posted a 1-1 mark in its latest edition and aims to improve this week. Week 4 lines tracked include Commanders -2 at Falcons. Last week, the Chiefs covered a 5.5-point spread before the line moved to 6.5 and 7 at some shops, while the Texans opened at 1.5 and did not move much in their loss to the Jaguars. Caesars Sportsbook provided the lines.
Analysts say the Week 4 picture is shaped in part by quarterback uncertainty in key matchups. The Falcons could lean on changes at quarterback, with Michael Penix Jr. having a rough showing that some observers view as supporting a benching, and there has been talk the Falcons could pursue Kirk Cousins for Week 4. Washington, meanwhile, leaned on Marcus Mariota in Week 3, but Jayden Daniels is described as a linchpin for the offense; Daniels’ Week 4 status was not officially ruled out until late last week.
In the other marquee matchup, Philadelphia is a 3-point favorite at Tampa Bay. The Buccaneers may be without Mike Evans and Chris Godwin, both dealing with hamstring injuries. If Evans is ruled out, Tampa Bay's offense could struggle to match Philadelphia, and any move to the 4.5 territory could provide a middle opportunity for bettors.
The piece also highlights context from The New York Post Betting, including input from Erich Richter, whose player-prop coverage has drawn attention for its results in recent seasons. Richter’s work is cited as part of the broader betting narrative surrounding Week 4.
As Week 4 approaches, bettors will watch line movements closely. The early moves reflect sharp money on some games and uncertainty in others, underscoring the ongoing challenge of predicting outcomes in a league where injuries, lineup changes and late-week news can shift the spread.
